AB064. P-35. Quantitative magnetic resonance cholangiopancreatography applications in primary sclerosing cholangitis and cholangiocarcinoma
نویسندگان
چکیده
منابع مشابه
Cholangiocarcinoma in primary sclerosing cholangitis
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease of unknown causes closely associated with ulcerative colitis. PSC is a progressive disease leading to liver failure and need for liver transplantation. Cholangiocarcinoma (CC) occurs in 10 20% of patients with PSC. The prognosis for CC is poor, even after liver transplantation. It is of great importance to identify PS...
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The protein encoded by the p53 tumour suppressor gene plays an important part in the regulation of cell growth. Abnormalities of this gene represent one of the most common genetic changes in the development of human cancers. This study investigated the expression of p53 protein in cholangiocarcinoma arising in association with primary sclerosing cholangitis (PSC). Of the 14 patients with cholan...
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Intrahepatic cholangiocarcinoma (ICC) is the second most common primary liver cancer after hepatocellular carcinoma (HCC). The risk of ICC is higher in patients with primary sclerosing cholangitis (PSC). To date, the cellular and molecular mechanism underlying the pathological progression of PSC and ICC is poorly understood. IKKa is part of the I B kinase (IKK) complex, which plays an important...
متن کاملChallenges of Cholangiocarcinoma Detection in Patients with Primary Sclerosing Cholangitis
Primary sclerosing cholangitis (PSC) is a chronic, cholestatic, idiopathic liver disease characterized by fibroobliterative inflammation of the hepatic bile ducts. In a clinically significant proportion of patients, PSC progresses to cirrhosis, end-stage liver disease, and in some cases, cholangiocarcinoma (CCA). The development of CCA in PSC is unpredictable, its surveillance and diagnosis com...
متن کاملPredicting cholangiocarcinoma in patients with primary sclerosing cholangitis before transplantation.
Patients with primary sclerosing cholangitis are at an increased risk of developing cholangiocarcinoma, which is difficult to diagnose because the biliary tree is already distorted. Eleven patients with primary sclerosing cholangitis who underwent orthotopic liver transplantation at this hospital were evaluated. Four patients had coincidental histologically proved cholangiocarcinoma. Patients w...
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ژورنال
عنوان ژورنال: HepatoBiliary Surgery and Nutrition
سال: 2019
ISSN: 2304-3881,2304-389X
DOI: 10.21037/hbsn.2019.ab064